Food and diet - PaoloBellavite14

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Food and diet

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DIET AND NUTRACEUTICSBellavite's research was repeatedly addressed also to the beneficial effects of diet on health.
>>(1998) Effects of
dietary fish oil and soy phosphatidylcholine on neutrophil fatty acid composition, superoxide release and adhesion.
>>(1999) Differential effects of dietary supplementation with fish oil or soy lecithin on human platelet adhesion
>>(2010) Stimulus-specific regulation of CD63 and CD203c membrane expression in human basophils by the flavonoid quercetin
>>(2011) Attività modulatoria del flavonoide naturale quercetina sulla funzione di basofili umani in vitro (ITALIAN)
>>(2015) Effects of dietary components on cancer of the digestive system

Here below the main reports on the effects on cancer are reported.
>>These are published in Italian and in English


THE FOLLOWING FIGURE ILLUSTRATES SOME OF THE HEALTHY FOODS CONTAINING ANTI-CANCER COMPONENTS. THE FIGURE IS LINKED TO A DETAILED TABLE.


Cancer is the second leading cause of death in developed countries and poor diet and physical inactivity are major risk factors in cancer-related deaths. Therefore, interventions to reduce levels of smoking, improve diet, and increase physical activity must become much higher priorities in the general population's health and health care systems. The consumption of fruit and vegetables exerts a preventive effect towards cancer and in recent years natural dietary agents have attracted great attention in the scientific community and among the general public. Foods contain active components that can influence the initiation and the progression of carcinogenesis, acting on pathways implied in cell proliferation, apoptosis and metastasis. The present review illustrates the main foods and their active components, including their antioxidant, cytotoxic and pro-apoptotic properties, with a particular focus on cancers of the digestive system.

Gli ultimi due decenni sono stati testimoni di un aumento di interesse della comunità scientifica verso i prodotti naturali e verso il loro impiego in oncologia. L’idea di usare prodotti alimentari e sostanze vegetali come medicine origina da studi epidemiologici che suggeriscono che l’abitudine alimentare vegetariana è associata a ridotto rischio di malattie tumorali, cardiovascolari e neurodegenerative. Attualmente le sostanze vegetali di potenziale uso antitumorale sono oggetto di molte ricerche di laboratorio e cliniche. La letteratura è molto vasta e impossibile da riportare interamente. È noto che molte molecole oggi usate come farmaci sono derivate da sostanze naturali, ma qui ci interessiamo solo delle sostanze presenti in estratti grezzi e dei loro principi attivi. La figura 1 illustra la varietà di molecole presenti in alcuni rappresentativi vegetali in cui sono stati dimostrati i principi attivi con proprietà citotossiche e citostatiche.

THE FOLLOWING FIGURES ILLUSTRATE SOME OF THE MECHANISMS OF ACTION OF SEVERAL NATURAL COMPONENTS ON THE CANCER CELLS. LEFT: INHIBITION OF PROLIFERATION; RIGHT: STIMULATION OF APOPTOSE. THE FIGURES ARE LINKED WITH LEGEND INCLUDING ABBREVIATION MEANING.

 
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